Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464366 | 0.79 | SLC22A12 (0.42) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL1464422 | 0.79 | NPC1 (0.42) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL20769713 | 0.70 | NPC1 (0.57) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL77451 | 0.68 | ATAD2 (0.61) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL20769721 | 0.67 | ALDH1A1 (0.52) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL12102170 | 0.65 | NPC1 (0.46) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL1464756 | 0.65 | NPC1 (0.46) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL20788543 | 0.65 | NPC1 (0.77) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL21484891 | 0.64 | ALDH1A1 (0.59) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL3790984 | 0.64 | NPC1 (0.66) | NPC1RAB9AKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |