SCHEMBL14309727

SCHEMBL14309727

C=C1OB(c2ccc(F)nc2)OC1(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074045 0.82 NOS3 (0.34)
SCHEMBL12647109 0.82
SCHEMBL12314754 0.82 DGAT1 (0.32)
SCHEMBL13100018 0.81 HCAR3 (0.34)
SCHEMBL13474635 0.80 LPL (0.38) LPLLIPG
SCHEMBL14231975 0.79 LPL (0.51) LPLLIPG
SCHEMBL10441880 0.78 DGAT1 (0.30)
SCHEMBL14316342 0.77 DGAT1 (0.49) LPLLIPG
SCHEMBL13100020 0.77 HCAR3 (0.38) LPLLIPG
SCHEMBL13100135 0.77 HCAR3 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008009435-A1 AMINO-PIPERIDINE DERIVATIVES AS CETP INHIBITORS NOVARTIS AG (CH) 2008-01-24 WO disclosed