Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13816280 | 0.86 | KIF11 (0.54) | KIF11GLAPEPDALDH1A1NPC1 | |
| SCHEMBL13315483 | 0.84 | GAA (0.61) | GLATSHRALDH1A1NPC1KDM4E | |
| SCHEMBL13315478 | 0.80 | PKM (0.54) | TSHRALDH1A1POLBNPC1KDM4E | |
| SCHEMBL6918008 | 0.80 | POLB (0.66) | KIF11TSHRRECQLPEPDALDH1A1 | |
| SCHEMBL3047568 | 0.77 | ALDH1A1 (0.60) | KIF11TSHRPEPDALDH1A1POLB | |
| SCHEMBL1954485 | 0.77 | KIF11 (0.52) | KIF11PEPDALDH1A1POLBNPC1 | |
| SCHEMBL6827233 | 0.77 | KIF11 (0.52) | KIF11GLAPEPDALDH1A1POLB | |
| SCHEMBL16160055 | 0.76 | POLB (0.49) | ALDH1A1POLBGAAMAPT | |
| SCHEMBL2755843 | 0.75 | KMT2A (0.59) | KIF11ALDH1A1POLBNPC1KDM4E | |
| SCHEMBL8781096 | 0.75 | KIF11 (0.50) | KIF11GLAPEPDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321001-B2 | Asthma and allergic inflammation modulators | AMGEN INC. (US) | 2008-01-22 | — | — | US | disclosed |