Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PEPD | P12955 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320359 | 0.86 | GNG2 (0.53) | MAPTTDP1POLBALDH1A1NPC1 | |
| SCHEMBL2855474 | 0.86 | TDP1 (0.52) | MAPTTDP1POLBALDH1A1NPC1 | |
| SCHEMBL11212757 | 0.85 | MAPT (0.47) | MAPTTDP1POLBALDH1A1NPC1 | |
| SCHEMBL2081736 | 0.85 | TDP1 (0.57) | MAPTTDP1POLBALDH1A1NPC1 | |
| SCHEMBL30483162 | 0.85 | TDP1 (0.57) | MAPTTDP1POLBALDH1A1NPC1 | |
| SCHEMBL6918008 | 0.84 | POLB (0.66) | KIF11MAPTPEPDPOLBALDH1A1 | |
| SCHEMBL10782684 | 0.81 | SMN1; SMN2 (0.52) | MAPTTDP1POLBALDH1A1CFTR | |
| SCHEMBL31314406 | 0.81 | SMN1; SMN2 (0.52) | MAPTTDP1POLBALDH1A1CFTR | |
| SCHEMBL9136264 | 0.81 | GPR35 (0.53) | MAPTTDP1POLBNPC1CFTR | |
| SCHEMBL1954485 | 0.81 | KIF11 (0.52) | KIF11MAPTPEPDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020189029-A1 | Agent and method for colouring keratin fibres | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | claimed |
| US-6740127-B2 | OXIDIZING AGENT, A 4,5-DIAMINOPYRAZOLE DERIVATIVE, AND A PHENYLUREA DERIVATIVE | WELLA AKTIENGELLSCHAFT (DE) | 2004-05-25 | — | — | US | disclosed |
| US-20020189029-A1 | Agent and method for colouring keratin fibres | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-12-19 | — | — | US | disclosed |
| EP-0979847-B1 | WATER-SOLUBLE TRISAZO COMPOUNDS, AQUEOUS INK COMPOSITION AND COLORED ARTICLE | NIPPON KAYAKU KK (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-6409810-B1 | STORAGE STABILITY; HIGH OPTICAL DENSITY; WATERPROOF AND LIGHT RESISTANCE; PENS; PRINTED IMAGES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-06-25 | — | — | US | disclosed |
| US-6194554-B1 | DYEING AND PRINTING MATERIALS CONTAINING CARBOXAMIDE GROUPS AND/OR CELLULOSIC MATERIALS BY APPLYING DISAZO DYE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |
| EP-0979847-A1 | WATER-SOLUBLE TRISAZO COMPOUNDS, AQUEOUS INK COMPOSITION AND COLORED ARTICLE | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2000-02-16 | — | — | EP | disclosed |
| EP-0514330-B1 | Azodyes | CIBA GEIGY AG (CH) | 1996-07-17 | — | — | EP | disclosed |
| EP-0426616-B1 | Reactive dyes, their preparation and their use | CIBA GEIGY AG (CH) | 1995-11-15 | — | — | EP | disclosed |
| US-5225545-A | Colorfast | CIBA-GEIGY CORPORATION (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0426616-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1991-05-08 | — | — | EP | disclosed |
| US-4906739-A | Fibre-reactive azo dyes containing a monofluororotriazine group | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0230210-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-12-13 | — | — | EP | disclosed |
| US-4866162-A | Fiber-reactive fluoro-triazine containing dyestuff | CIBA-GEIGY CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |
| US-4845203-A | FOR CELLULOSE FIBERS | CIBA-GEIGY CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| EP-0261079-A1 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1988-03-23 | — | — | EP | disclosed |
| EP-0242850-A1 | Water soluble monoazo compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-10-28 | — | — | EP | disclosed |
| EP-0230210-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1987-07-29 | — | — | EP | disclosed |
| EP-0159291-A1 | Ink composition for the ink-jet printing process | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0011873-A1 | Polyazo dyestuffs, their preparation and application to the dyeing of cellulose materials | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020189029-A1 | Agent and method for colouring keratin fibres | KRT18, OAT, COXFA4L2 | KIF11 317/4885MAPT 693/4885TDP1 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.