Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | FPR3 | P25089 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312680 | 0.91 | GRIN2B (0.47) | GAATDP1HPGDPKMHTT | |
| SCHEMBL14312440 | 0.86 | LMNA (0.45) | ALDH1A1KDM4EPKMKMT2A | |
| SCHEMBL14312528 | 0.86 | USP2 (0.52) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL2472775 | 0.86 | KMT2A (0.48) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL2472772 | 0.86 | KMT2A (0.48) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL14312514 | 0.85 | KDM4E (0.49) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL14312471 | 0.83 | TAS1R3 (0.46) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL14312589 | 0.83 | ALDH1A1 (0.58) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL14312275 | 0.83 | KMT2A (0.51) | ALDH1A1GAAKDM4ETDP1SMN1; SMN2 | |
| SCHEMBL14312438 | 0.82 | KDM4E (0.41) | ALDH1A1KDM4EKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228065-B1 | Heterocyclo inhibitors of potassium channel function | BRISTOL MYERS SQUIBB CO (US) | 2012-12-26 | — | — | EP | claimed |