Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 6/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312611 | 0.93 | CYP2D6 (0.61) | USP2CYP2D6NPC1CYP3A4TSHR | |
| SCHEMBL14312471 | 0.88 | TAS1R3 (0.46) | NAMPTTSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14312548 | 0.87 | CYP2D6 (0.57) | USP2CYP2D6CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL14312448 | 0.87 | CYP2D6 (0.54) | USP2CYP2D6NPC1CYP3A4TSHR | |
| SCHEMBL14312514 | 0.86 | KDM4E (0.49) | NAMPTSMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL14312549 | 0.86 | ALDH1A1 (0.44) | NAMPTSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL2469507 | 0.85 | USP2 (0.53) | USP2CYP2D6NPC1CYP3A4NAMPT | |
| SCHEMBL14312275 | 0.84 | KMT2A (0.51) | TSHRSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL14312589 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1MAPK1KDM4EGAA | |
| SCHEMBL14312598 | 0.83 | DGAT2 (0.46) | ALDH1A1KDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228065-B1 | Heterocyclo inhibitors of potassium channel function | BRISTOL MYERS SQUIBB CO (US) | 2012-12-26 | — | — | EP | claimed |