Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 15/20 | 0.46 |
| ▸ | MGAT2 | Q10469 | 5/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312315 | 0.91 | GRIN2B (0.49) | APPMC4RHRH3TDP1 | |
| SCHEMBL14312347 | 0.87 | ALDH1A1 (0.46) | DGAT2APPHRH3KDM4EALDH1A1 | |
| SCHEMBL2469571 | 0.87 | CHRM5 (0.45) | DGAT2MGAT2APPMC4R | |
| SCHEMBL14312275 | 0.85 | KMT2A (0.51) | KDM4EALDH1A1GAATDP1 | |
| SCHEMBL14312528 | 0.83 | USP2 (0.52) | KDM4EALDH1A1GAATDP1 | |
| SCHEMBL14312594 | 0.82 | CHRM5 (0.50) | APPHRH3ALDH1A1GAA | |
| SCHEMBL14312542 | 0.82 | HRH3 (0.48) | APPHRH3ALDH1A1 | |
| SCHEMBL14312514 | 0.82 | KDM4E (0.49) | KDM4EALDH1A1GAATDP1 | |
| SCHEMBL14312549 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1GAATDP1 | |
| SCHEMBL14312471 | 0.80 | TAS1R3 (0.46) | KDM4EALDH1A1GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2228065-B1 | Heterocyclo inhibitors of potassium channel function | BRISTOL MYERS SQUIBB CO (US) | 2012-12-26 | — | — | EP | claimed |