Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL658204 | 0.95 | TRIM24 (0.36) | TRIM24TRIM33ALDH1A1KMT2AMEN1 | |
| SCHEMBL46361 | 0.90 | KMT2A (0.34) | TRIM24TRIM33ALDH1A1KMT2AMEN1 | |
| SCHEMBL14506033 | 0.88 | TRIM24 (0.41) | TRIM24TRIM33ALDH1A1TSHRKDM4E | |
| Water SCHEMBL31387323 | 0.87 | ALDH1A1 (0.33) | TRIM24TRIM33ALDH1A1KMT2AMEN1 | |
| SCHEMBL7523454 | 0.86 | GAA (0.32) | — | |
| SCHEMBL13276962 | 0.86 | TRIM24 (0.39) | TRIM24TRIM33ALDH1A1KMT2AMEN1 | |
| SCHEMBL8603903 | 0.82 | ALDH1A1 (0.46) | TRIM24TRIM33ALDH1A1KMT2AMEN1 | |
| SCHEMBL31715737 | 0.81 | GAA (0.33) | ALDH1A1KMT2AMEN1CYP2C9KDM4E | |
| SCHEMBL12350017 | 0.80 | TRIM24 (0.43) | TRIM24TRIM33ALDH1A1KMT2AMEN1 | |
| SCHEMBL13500408 | 0.79 | MEN1 (0.34) | TRIM24TRIM33ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115266606-A | Method for judging substance components of hydrothermal liquefaction water-phase product and application | 中国农业大学 | 2022-11-01 | — | — | CN | disclosed |
| US-8993556-B2 | Resorcinol derivatives as HSP90 inhibitors | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2015-03-31 | — | — | US | disclosed |
| EP-2421833-B1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2015-01-14 | — | — | EP | disclosed |
| EP-2590985-B1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LTD (IE) | 2014-05-14 | — | — | EP | disclosed |
| US-8580962-B2 | Spiroheterocyclic compounds as mGlu5 antagonists | RECORDATI IRELAND LTD. (IT) | 2013-11-12 | — | — | US | disclosed |
| EP-2590985-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | Recordati Ireland Limited (IE) | 2013-05-15 | — | — | EP | disclosed |
| US-20120059015-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LTD. (IT) | 2012-03-08 | — | — | US | disclosed |
| EP-2421833-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2012-02-29 | — | — | EP | disclosed |
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-02-23 | — | — | US | disclosed |
| WO-2012004400-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | RECORDATI IRELAND LIMITED (IE) | 2012-01-12 | — | — | WO | disclosed |
| WO-2009056233-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AND UNSUBSTITUTED CYCLOHEXANONE MONOKETALS | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009056233-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AND UNSUBSTITUTED CYCLOHEXANONE MONOKETALS | BAYER CROPSCIENCE AG (DE) | 2009-05-07 | — | — | WO | disclosed |
| EP-2055693-A1 | Method for manufacturing substituted and unsubstituted cyclohexanone monoketales | Bayer CropScience AG (DE) | 2009-05-06 | — | — | EP | disclosed |
| EP-2055693-A1 | Method for manufacturing substituted and unsubstituted cyclohexanone monoketales | Bayer CropScience AG (DE) | 2009-05-06 | — | — | EP | disclosed |
| US-7279601-B2 | Optically active α-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2007-10-09 | — | — | US | disclosed |
| WO-2007062316-A2 | TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR ANTI-MANNICH REACTIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070117986-A1 | TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR anti-MANNICH REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2007-05-24 | — | — | US | disclosed |
| US-20070117986-A1 | TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR anti-MANNICH REACTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2007-05-24 | — | — | US | disclosed |
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | TOKYO UNIVERSITY OF SCIENCE, CENTER FOR SCIENCE AND TECHNOLOGY EXCHANGE (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1661885-A1 | OPTICALLY ACTIVE ALPHA-AMINOOXYKETONE DERIVATIVES AND PROCESS FOR PRODUCTION THEREOF | Tokyo University of Science (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90AB2P | TRIM24 1665/4885TRIM33 847/4885ALDH1A1 1996/4885 |
| US-20060293525-A1 | Optically active alpha-aminooxyketone derivatives and process for production thereof | ALDH7A1, ASPH, KMO | TRIM24 2275/4885TRIM33 4390/4885ALDH1A1 71/4885 |
| US-20070117986-A1 | TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR anti-MANNICH REACTIONS | HRH4, NR1I3, NR1I2 | TRIM24 3865/4885TRIM33 4069/4885ALDH1A1 810/4885 |
| US-20120059015-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS AS MGLU5 ANTAGONISTS | GRM5, GPR65, GRIK5 | TRIM24 4332/4885TRIM33 4107/4885ALDH1A1 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.