Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1035038 | 0.83 | HSD17B2 (0.44) | — | |
| SCHEMBL12955904 | 0.70 | APLNR (0.33) | — | |
| SCHEMBL1038945 | 0.69 | HSD17B2 (0.41) | — | |
| SCHEMBL1037086 | 0.69 | HSD17B2 (0.41) | — | |
| SCHEMBL1093939 | 0.68 | CCR9 (0.52) | — | |
| SCHEMBL12955953 | 0.64 | ALDH1A1 (0.39) | KMT2ALRRK2 | |
| SCHEMBL1037648 | 0.63 | HSD17B2 (0.50) | — | |
| SCHEMBL1035744 | 0.62 | CCR9 (0.47) | — | |
| SCHEMBL1034965 | 0.61 | HSD17B2 (0.41) | — | |
| SCHEMBL1038886 | 0.61 | HSD17B2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008375-A2 | TRIAZOLYL PYRIDYL BENZENESULFONAMIDES AS CCR2 OR CCR9 MODULATORS FOR THE TREATMENT OF INFLAMMATION | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |