Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14485435 | 0.87 | KLKB1 (0.47) | METAP2METAP1CPB2F12KLKB1 | |
| SCHEMBL3154833 | 0.84 | MASP2 (0.48) | METAP2METAP1CPB2MASP2CPB1 | |
| SCHEMBL1431488 | 0.83 | MALT1 (0.39) | MASP2KCNH2EPHX2 | |
| SCHEMBL1431835 | 0.83 | CPB2 (0.43) | METAP2METAP1CPB2MASP2F12 | |
| SCHEMBL3144125 | 0.83 | CPB2 (0.43) | METAP2METAP1CPB2MASP2F12 | |
| SCHEMBL1431704 | 0.82 | MASP2 (0.43) | CPB2MASP2KLKB1 | |
| SCHEMBL1431986 | 0.81 | MASP2 (0.42) | MASP2KCNH2 | |
| SCHEMBL1432596 | 0.81 | MASP2 (0.39) | MASP2KCNH2EPHX2 | |
| SCHEMBL1901816 | 0.79 | MASP2 (0.39) | CPB2MASP2KCNH2SLC6A3 | |
| SCHEMBL1432473 | 0.78 | MASP2 (0.38) | CPB2MASP2KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |