Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | FURIN | P09958 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901816 | 0.89 | MASP2 (0.39) | MASP2TSHRF7FURINCYP3A4 | |
| SCHEMBL1432133 | 0.88 | MASP2 (0.40) | MASP2NAMPT | |
| SCHEMBL1432596 | 0.86 | MASP2 (0.39) | MASP2TSHRFURINKCNH2NAMPT | |
| SCHEMBL1432545 | 0.86 | NAMPT (0.44) | MASP2NPSR1NAMPT | |
| SCHEMBL1431488 | 0.81 | MALT1 (0.39) | MASP2KCNH2 | |
| SCHEMBL1431704 | 0.81 | MASP2 (0.43) | MASP2NAMPTCPB2 | |
| SCHEMBL1907931 | 0.81 | BACE1 (0.40) | MASP2NAMPTCPB2 | |
| SCHEMBL3154110 | 0.80 | KLKB1 (0.42) | MASP2NPSR1TSHRF7FURIN | |
| SCHEMBL1432471 | 0.80 | KLKB1 (0.42) | MASP2NPSR1TSHRF7FURIN | |
| SCHEMBL1432287 | 0.80 | MASP2 (0.39) | MASP2NAMPTCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | claimed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | claimed |