Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905450 | 0.88 | MASP2 (0.43) | MASP2NAMPTBACE1CARM1PRMT6 | |
| SCHEMBL1431844 | 0.88 | MASP2 (0.45) | MASP2NAMPTBACE1CARM1PRMT6 | |
| SCHEMBL1901851 | 0.86 | MASP2 (0.41) | MASP2NAMPTMEN1KMT2ABACE1 | |
| SCHEMBL1901410 | 0.85 | MASP2 (0.41) | MASP2NAMPTCPB2BACE1HDAC1 | |
| SCHEMBL1904477 | 0.85 | MASP2 (0.42) | MASP2NAMPTCARM1PRMT6HDAC1 | |
| SCHEMBL1432468 | 0.82 | CYP3A4 (0.42) | MASP2NAMPTCARM1PRMT6HDAC1 | |
| SCHEMBL4303211 | 0.78 | NAMPT (0.46) | MASP2NAMPTEPHX2CARM1PRMT6 | |
| SCHEMBL1902783 | 0.72 | MASP2 (0.41) | MASP2NAMPTCPB2BACE1HDAC1 | |
| SCHEMBL1900464 | 0.72 | MASP2 (0.41) | MASP2NAMPTMEN1KMT2ABACE1 | |
| SCHEMBL1907939 | 0.72 | METAP2 (0.37) | BACE1CARM1PRMT6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |