Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902464 | 1.00 | MASP2 (0.39) | MASP2PDPK1NAMPTBACE1CACNA1G | |
| SCHEMBL1904701 | 0.89 | NAMPT (0.45) | MASP2PDPK1NAMPTGABRPGABRD | |
| SCHEMBL1907783 | 0.89 | PDPK1 (0.38) | MASP2PDPK1NAMPTBACE1TLR2 | |
| SCHEMBL1431876 | 0.89 | MASP2 (0.43) | MASP2PDPK1NAMPTBACE1CACNA1G | |
| SCHEMBL1901816 | 0.86 | MASP2 (0.39) | MASP2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1432510 | 0.86 | MASP2 (0.38) | MASP2PDPK1NAMPTBACE1CACNA1G | |
| SCHEMBL1903992 | 0.85 | NAMPT (0.42) | MASP2PDPK1NAMPTTLR2 | |
| SCHEMBL1901340 | 0.85 | PDPK1 (0.39) | MASP2PDPK1NAMPTBACE1TLR2 | |
| SCHEMBL1431965 | 0.84 | EHMT2 (0.43) | MASP2PDPK1NAMPTCACNA1GCACNA1H | |
| SCHEMBL1902876 | 0.84 | BACE1 (0.40) | MASP2PDPK1NAMPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |