Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25449261 | 0.89 | ALDH1A1 (0.40) | SMN1; SMN2MLNRALDH1A1HPGDKDM4E | |
| SCHEMBL30300617 | 0.89 | TPSAB1 (0.33) | — | |
| SCHEMBL13545642 | 0.89 | ALDH1A1 (0.40) | SMN1; SMN2MLNRALDH1A1HPGDKDM4E | |
| SCHEMBL31408170 | 0.89 | TPSAB1 (0.33) | — | |
| SCHEMBL4610136 | 0.86 | — | — | |
| SCHEMBL4405242 | 0.80 | MMP1 (0.38) | SMN1; SMN2MLNRALDH1A1HPGDKDM4E | |
| SCHEMBL14214481 | 0.78 | KDM4E (0.34) | SMN1; SMN2MLNRALDH1A1HPGDKDM4E | |
| SCHEMBL12869910 | 0.75 | HDAC8 (0.47) | SMN1; SMN2MLNRALDH1A1HPGDKDM4E | |
| SCHEMBL14457494 | 0.75 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL6554343 | 0.74 | TSHR (0.40) | ALDH1A1MEN1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013984-A2 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OPHTHALMIC DISEASE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-01-31 | — | — | WO | disclosed |