Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 2/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431568 | 0.90 | TACR1 (0.44) | TACR1ITGB1ITGA4XIAPMASP2 | |
| SCHEMBL1432215 | 0.88 | TACR1 (0.45) | TACR1XIAPMASP2 | |
| SCHEMBL1432083 | 0.85 | TACR1 (0.47) | TACR1ITGB1ITGA4XIAPMASP2 | |
| SCHEMBL1432037 | 0.85 | TACR1 (0.47) | TACR1ITGB1ITGA4XIAPMASP2 | |
| Hydrochloric Acid SCHEMBL3256738 | 0.85 | TACR1 (0.46) | TACR1XIAP | |
| SCHEMBL1434992 | 0.84 | ALDH1A1 (0.50) | TACR1LMNAXIAPMEN1KMT2A | |
| SCHEMBL1433071 | 0.84 | ALDH1A1 (0.50) | TACR1LMNAXIAPMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL1433925 | 0.81 | XIAP (0.45) | TACR1ITGB1ITGA4XIAPMEN1 | |
| SCHEMBL1432571 | 0.80 | LCK (0.41) | TACR1ITGB1ITGA4MASP2MEN1 | |
| SCHEMBL1432409 | 0.80 | CTSL (0.48) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |