Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432824 | 0.92 | MASP2 (0.41) | MASP2ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL1432532 | 0.91 | MEN1 (0.48) | MASP2ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL1431814 | 0.91 | MEN1 (0.48) | MASP2ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL1432409 | 0.91 | CTSL (0.48) | ITGB1ITGA4 | |
| SCHEMBL1431568 | 0.91 | TACR1 (0.44) | MASP2ITGB1ITGA4PPIBTACR1 | |
| SCHEMBL1432349 | 0.90 | EPHX2 (0.45) | — | |
| SCHEMBL1432180 | 0.90 | DPP4 (0.40) | MASP2MEN1KMT2APPIB | |
| SCHEMBL1431638 | 0.90 | DPP4 (0.40) | MASP2MEN1KMT2APPIB | |
| SCHEMBL1433004 | 0.90 | PPIB (0.43) | MASP2MEN1KMT2APPIB | |
| Hydrochloric Acid SCHEMBL1432515 | 0.89 | DPP4 (0.40) | MASP2MEN1KMT2APPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |