Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 4/20 | 0.47 |
| ▸ | CTSC | P53634 | 3/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432632 | 0.89 | MASP2 (0.47) | MASP2CTSCGHSRF2HTR2C | |
| SCHEMBL1432216 | 0.87 | MASP2 (0.44) | MASP2CTSCGHSRF2HTR2C | |
| SCHEMBL1432411 | 0.86 | MASP2 (0.46) | MASP2CTSCGHSRF2HTR2C | |
| SCHEMBL1432888 | 0.86 | CTSL (0.49) | MASP2CTSCF2HTR2CHTR2B | |
| SCHEMBL1431930 | 0.85 | MASP2 (0.45) | MASP2CTSCF2HTR2CHTR2B | |
| SCHEMBL1432735 | 0.84 | MASP2 (0.46) | MASP2CTSCF2HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1432057 | 0.84 | MASP2 (0.44) | MASP2CTSCF2HTR2CHTR2B | |
| SCHEMBL1432761 | 0.82 | MASP2 (0.44) | MASP2CTSCHTR2CHTR2BCTSK | |
| SCHEMBL1431988 | 0.81 | TACR1 (0.44) | MASP2 | |
| SCHEMBL1432138 | 0.80 | TACR1 (0.45) | MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |