Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 4/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432231 | 0.89 | MASP2 (0.47) | MASP2F2GHSRCTSCHTR2C | |
| SCHEMBL1432411 | 0.87 | MASP2 (0.46) | MASP2F2GHSRCTSCHTR2C | |
| SCHEMBL1432735 | 0.84 | MASP2 (0.46) | MASP2F2CTSCHTR2CHTR2B | |
| SCHEMBL1432888 | 0.84 | CTSL (0.49) | MASP2F2CTSCHTR2CHTR2B | |
| SCHEMBL1432761 | 0.82 | MASP2 (0.44) | MASP2CTSCHTR2CHTR2B | |
| SCHEMBL1432216 | 0.82 | MASP2 (0.44) | MASP2F2GHSRFNTAPGGT1B | |
| SCHEMBL1433336 | 0.81 | TACR1 (0.46) | MASP2F2FNTAPGGT1BPLG | |
| SCHEMBL1432145 | 0.80 | TACR1 (0.46) | MASP2F2FNTAPGGT1BPLG | |
| SCHEMBL1907859 | 0.79 | CYP3A4 (0.42) | MASP2FNTAPGGT1BOPRD1 | |
| SCHEMBL1902805 | 0.79 | OPRD1 (0.46) | MASP2CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |