Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.49 |
| ▸ | CTSV | O60911 | 6/20 | 0.49 |
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | MASP2 | O00187 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432216 | 0.90 | MASP2 (0.44) | CTSLCTSVCTSSCTSKMASP2 | |
| SCHEMBL1432761 | 0.88 | MASP2 (0.44) | CTSKMASP2HTR2CCTSCHTR2B | |
| SCHEMBL1431930 | 0.87 | MASP2 (0.45) | CTSLMASP2F2HTR2CCTSC | |
| Hydrochloric Acid SCHEMBL1432057 | 0.87 | MASP2 (0.44) | CTSLMASP2F2HTR2CCTSC | |
| SCHEMBL1432231 | 0.86 | MASP2 (0.47) | CTSKMASP2F2HTR2CCTSC | |
| SCHEMBL1431919 | 0.86 | MASP2 (0.45) | MASP2HTR2CCTSCHTR2B | |
| SCHEMBL1432735 | 0.85 | MASP2 (0.46) | CTSKMASP2F2HTR2CCTSC | |
| SCHEMBL1432632 | 0.84 | MASP2 (0.47) | MASP2F2HTR2CCTSCHTR2B | |
| SCHEMBL1432409 | 0.81 | CTSL (0.48) | CTSLCTSVCTSSCTSKF2 | |
| SCHEMBL1432411 | 0.81 | MASP2 (0.46) | CTSLCTSSCTSKMASP2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |