Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | MASP2 | O00187 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432977 | 0.91 | F2 (0.49) | F2CTSBITGB1ITGA4 | |
| SCHEMBL1432803 | 0.90 | CTSB (0.41) | ALDH1A1MAPTCRHBPCRHR2MASP2 | |
| SCHEMBL1432630 | 0.89 | DPP4 (0.39) | ALDH1A1MAPTMASP2F2MEN1 | |
| SCHEMBL1431769 | 0.89 | DPP4 (0.39) | ALDH1A1MAPTMASP2F2MEN1 | |
| SCHEMBL1432980 | 0.87 | MEN1 (0.47) | ALDH1A1MASP2F2ITGB1ITGA4 | |
| SCHEMBL1431973 | 0.87 | MEN1 (0.47) | ALDH1A1MASP2F2ITGB1ITGA4 | |
| SCHEMBL1432174 | 0.82 | DPP4 (0.38) | ALDH1A1MASP2F2MEN1KMT2A | |
| SCHEMBL1432074 | 0.82 | DPP4 (0.38) | ALDH1A1MASP2F2MEN1KMT2A | |
| SCHEMBL1432037 | 0.82 | TACR1 (0.47) | MASP2F2ITGB1ITGA4 | |
| SCHEMBL1432083 | 0.82 | TACR1 (0.47) | MASP2F2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |