Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.41 |
| ▸ | MASP2 | O00187 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432319 | 0.91 | KMT2A (0.43) | MASP2CTSSCTSKALDH1A1MEN1 | |
| SCHEMBL1432409 | 0.91 | CTSL (0.48) | CTSBCTSLCTSSCTSKCTSV | |
| SCHEMBL1433055 | 0.91 | KMT2A (0.43) | MASP2CTSSCTSKALDH1A1MEN1 | |
| SCHEMBL1432824 | 0.91 | MASP2 (0.41) | MASP2ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL1432148 | 0.90 | KMT2A (0.43) | ALDH1A1MEN1KMT2AKLKB1PPIB | |
| SCHEMBL1432743 | 0.90 | ALDH1A1 (0.39) | CTSBMASP2ALDH1A1MAPTCRHBP | |
| SCHEMBL1432377 | 0.89 | MAPK14 (0.45) | CTSLKMT2A | |
| SCHEMBL1432180 | 0.88 | DPP4 (0.40) | MASP2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1431638 | 0.88 | DPP4 (0.40) | MASP2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1431568 | 0.88 | TACR1 (0.44) | MASP2CTSLITGB1ITGA4KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |