Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.49 |
| ▸ | CTSL | P07711 | 9/20 | 0.47 |
| ▸ | CTSV | O60911 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 8/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432743 | 0.91 | ALDH1A1 (0.39) | F2ITGB1ITGA4CTSB | |
| SCHEMBL1432409 | 0.91 | CTSL (0.48) | F2CTSLCTSVCTSSCTSK | |
| SCHEMBL1432630 | 0.90 | DPP4 (0.39) | F2 | |
| SCHEMBL1431769 | 0.90 | DPP4 (0.39) | F2 | |
| SCHEMBL1432334 | 0.89 | F2 (0.46) | F2CTSLCTSVCTSSCTSK | |
| SCHEMBL1433005 | 0.89 | CTSV (0.47) | F2CTSLCTSVCTSSCTSK | |
| SCHEMBL1431973 | 0.86 | MEN1 (0.47) | F2ITGB1ITGA4 | |
| SCHEMBL1432980 | 0.86 | MEN1 (0.47) | F2ITGB1ITGA4 | |
| SCHEMBL1432037 | 0.84 | TACR1 (0.47) | F2ITGB1ITGA4 | |
| SCHEMBL1432083 | 0.84 | TACR1 (0.47) | F2ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |