SCHEMBL14327643

SCHEMBL14327643

C=Cc1oc2cc(C)ccc2c1/C=C\C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
HPGD P15428 1/20 0.36
APP P05067 1/20 0.31
CDC25A P30304 1/20 0.31
CDC25C P30307 1/20 0.31
ALPG P10696 1/20 0.31
TP53 P04637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26840950 0.88 MAOB (0.36) MAOBALDH1A1GAAHPGDAPP
SCHEMBL18574501 0.88 ALPG (0.39) ALDH1A1HPGDALPGTP53TDP1
SCHEMBL24285628 0.80 IKBKE (0.36)
SCHEMBL12646572 0.79 L3MBTL1 (0.37) ALDH1A1HPGD
SCHEMBL13220852 0.77 MAOB (0.40) MAOBALDH1A1GAAHPGDAPP
SCHEMBL21131632 0.76 ALDH1A1 (0.34) ALDH1A1
SCHEMBL22376496 0.76 CA1 (0.32)
SCHEMBL21883464 0.75 MAPT (0.39) ALDH1A1HPGDALPGTP53TDP1
SCHEMBL21776181 0.74 SMN1; SMN2 (0.41) ALDH1A1GAAHPGDALPG
SCHEMBL21020698 0.73 MMP12 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230023360-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-26 US disclosed
US-20210175444-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION FOR INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2021-06-10 US disclosed
EP-3190164-B1 COMPOSITION, THIN FILM INCLUDING THE COMPOSITION, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE COMPOSITION OR THE THIN FILM SAMSUNG ELECTRONICS CO LTD (KR) 2019-07-24 EP disclosed
EP-2318417-B1 COMPOUND COMPRISING PHENYL PYRIDINE UNITS GEN ELECTRIC (US) 2012-12-26 EP disclosed