Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14327802 | 0.89 | ALOX5 (0.51) | HSD17B1HSD17B2ESR2ESR1ALOX5 | |
| SCHEMBL14327794 | 0.85 | MCL1 (0.54) | HSD17B1HSD17B2ALOX5GPR84CYP1A2 | |
| SCHEMBL14327785 | 0.84 | GPR84 (0.50) | HSD17B1HSD17B2ESR2ESR1ALOX5 | |
| SCHEMBL29510114 | 0.81 | MEN1 (0.58) | HSD17B1HSD17B2ALOX5GPR84MEN1 | |
| SCHEMBL3262604 | 0.81 | MEN1 (0.58) | HSD17B1HSD17B2ALOX5GPR84MEN1 | |
| SCHEMBL30275493 | 0.81 | MEN1 (0.58) | HSD17B1HSD17B2ALOX5GPR84MEN1 | |
| SCHEMBL12786270 | 0.80 | NQO1 (0.46) | HSD17B1HSD17B2ESR2ALOX5GPR84 | |
| SCHEMBL29026237 | 0.79 | MEN1 (0.52) | HSD17B1HSD17B2ESR2ESR1ALOX5 | |
| SCHEMBL14327803 | 0.79 | MEN1 (0.48) | ALOX5GPR84CYP1A2MEN1KMT2A | |
| SCHEMBL24434313 | 0.79 | ALOX5 (0.70) | HSD17B1HSD17B2ESR2ESR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420847-B2 | Bis-phosphate compound and asymmetric reaction using the same | NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420847-B2 | Bis-phosphate compound and asymmetric reaction using the same | NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | API CORPORATION (JP) | 2012-12-27 | — | — | US | disclosed |
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | API CORPORATION (JP) | 2012-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120330038-A1 | BIS-PHOSPHATE COMPOUND AND ASYMMETRIC REACTION USING THE SAME | AASDHPPT, ALDH7A1, ATIC | HSD17B1 962/4885HSD17B2 1377/4885ESR2 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.