Sugi Predict

Sugi Predict / Compounds / SCHEMBL14328640

SCHEMBL14328640

SCHEMBL14328640

O=C(O)c1ccc(/C=C/c2cc(/C=C/c3ccc(C(=O)O)cc3)cc(/C=C/c3ccc(C(=O)O)cc3)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.60
▸ TP53 P04637 2/20 0.57
▸ TSHR P16473 1/20 0.57
▸ FBP1 P09467 1/20 0.57
▸ RARA P10276 2/20 0.54
▸ RARB P10826 2/20 0.54
▸ RARG P13631 2/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ TTR P02766 2/20 0.53
▸ SRD5A2 P31213 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ PTPN2 P17706 2/20 0.50
▸ PTPN1 P18031 2/20 0.50
▸ PTPN6 P29350 2/20 0.50
▸ MAPT P10636 2/20 0.50
▸ HDAC1 Q13547 1/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ BLM P54132 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8653418 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL9078494 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL9339856 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL9681086 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL69167 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL9681088 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL2126364 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL69166 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
SCHEMBL2615887 0.93 ALDH1A1 (0.68) ALDH1A1TP53TSHRFBP1RARA
Hydrochloric Acid SCHEMBL994965 0.90 ALDH1A1 (0.65) ALDH1A1TP53TSHRFBP1RARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030774-B2 Surface-modified inorganic nitride, composition, thermally conductive material, and device with thermally conductive layer FUJIFILM CORPORATION (JP) 2024-07-09 — — US disclosed
US-12030774-B2 Surface-modified inorganic nitride, composition, thermally conductive material, and device with thermally conductive layer FUJIFILM CORPORATION (JP) 2024-07-09 — — US disclosed
US-10793495-B2 Synthesis of polyaryl substituted aryl compounds BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2020-10-06 — — US disclosed
US-20200215233-A1 ANTIMICROBIAL COATING BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2020-07-09 — — US disclosed
US-10696620-B2 Antimicrobial compounds BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2020-06-30 — — US disclosed
US-20200180957-A1 SURFACE-MODIFIED INORGANIC NITRIDE, COMPOSITION, THERMALLY CONDUCTIVE MATERIAL, AND DEVICE WITH THERMALLY CONDUCTIVE LAYER FUJIFILM CORPORATION (JP) 2020-06-11 — — US disclosed
US-20190328691-A1 ANTIBIOTIC THERAPY BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2019-10-31 — — US disclosed
WO-2019036759-A1 ANTIMICROBIAL COATING BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2019-02-28 — — WO disclosed
US-20180215687-A1 SYNTHESIS OF ARYL COMPOUNDS BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2018-08-02 — — US disclosed
US-20180215687-A1 SYNTHESIS OF ARYL COMPOUNDS BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2018-08-02 — — US disclosed
WO-2017045019-A1 ANTIBIOTIC THERAPY BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2017-03-23 — — WO disclosed
WO-2017027933-A1 SYNTHESIS OF ARYL COMPOUNDS BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2017-02-23 — — WO disclosed
US-20170029359-A1 ANTIMICROBIAL COMPOUNDS THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2017-02-02 — — US disclosed
US-20170029359-A1 ANTIMICROBIAL COMPOUNDS THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2017-02-02 — — US disclosed
US-20150189873-A1 ANTIMICROBIAL COMPOUNDS BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2015-07-09 — — US disclosed
US-20150189873-A1 ANTIMICROBIAL COMPOUNDS BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) 2015-07-09 — — US disclosed
US-9023892-B2 Antimicrobial compounds Boulos, Ramiz (AU) 2015-05-05 — — US disclosed
US-9023892-B2 Antimicrobial compounds Boulos, Ramiz (AU) 2015-05-05 — — US disclosed
US-20120329871-A1 ANTIMICROBIAL COMPOUNDS THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2012-12-27 — — US disclosed
US-20120329871-A1 ANTIMICROBIAL COMPOUNDS THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2012-12-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10793495-B2 Synthesis of polyaryl substituted aryl compounds UTS2R, UBTF, UGT1A1 ALDH1A1 521/4885TP53 2737/4885TSHR 952/4885
US-10696620-B2 Antimicrobial compounds MRPL21, SPOUT1, MPO ALDH1A1 2054/4885TP53 4133/4885TSHR 4275/4885
US-20180215687-A1 SYNTHESIS OF ARYL COMPOUNDS UTS2R, UGT1A1, NAT1 ALDH1A1 145/4885TP53 2602/4885TSHR 530/4885
US-20190328691-A1 ANTIBIOTIC THERAPY PEPD, NRDC, AAAS ALDH1A1 2793/4885TP53 3153/4885TSHR 3794/4885
US-20120329871-A1 ANTIMICROBIAL COMPOUNDS DPM1, NACA, CLPP ALDH1A1 2802/4885TP53 3606/4885TSHR 4333/4885
US-20170029359-A1 ANTIMICROBIAL COMPOUNDS MRPL21, SPOUT1, MPO ALDH1A1 2054/4885TP53 4133/4885TSHR 4275/4885
US-20150189873-A1 ANTIMICROBIAL COMPOUNDS DPM1, NACA, CLPP ALDH1A1 2802/4885TP53 3606/4885TSHR 4333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.