Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1432215 | 0.91 | TACR1 (0.45) | F2MASP2TACR1 | |
| SCHEMBL1432409 | 0.91 | CTSL (0.48) | CTSVCTSLCTSSCTSKF2 | |
| SCHEMBL1431634 | 0.90 | MEN1 (0.41) | MASP2KMT2ATACR1 | |
| SCHEMBL1432518 | 0.90 | MEN1 (0.41) | MASP2KMT2ATACR1 | |
| SCHEMBL1431672 | 0.89 | KMT2A (0.42) | MASP2KMT2A | |
| SCHEMBL1432977 | 0.89 | F2 (0.49) | CTSVCTSLCTSSCTSKF2 | |
| SCHEMBL1432054 | 0.87 | MEN1 (0.40) | MASP2KMT2A | |
| SCHEMBL1431881 | 0.87 | MASP2 (0.41) | ITGB1ITGA4MASP2KMT2ATACR1 | |
| SCHEMBL1432138 | 0.87 | TACR1 (0.45) | MASP2TACR1 | |
| SCHEMBL1432069 | 0.86 | MEN1 (0.49) | ITGB1ITGA4MASP2KMT2ATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |