Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.53 |
| ▸ | MASP2 | O00187 | 5/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434232 | 0.88 | F2 (0.51) | F2MASP2KLKB1CTSL | |
| SCHEMBL1432955 | 0.86 | KLKB1 (0.54) | F2MASP2KLKB1CTSLMAPK14 | |
| SCHEMBL1434049 | 0.85 | KLKB1 (0.47) | F2MASP2KLKB1 | |
| SCHEMBL1433255 | 0.85 | F2 (0.52) | F2MASP2CTSLMAPK14 | |
| SCHEMBL1434709 | 0.84 | F2 (0.51) | F2MASP2KLKB1 | |
| SCHEMBL1434273 | 0.82 | F2 (0.50) | F2MASP2KLKB1 | |
| SCHEMBL1434686 | 0.81 | MCHR1 (0.55) | F2MASP2CTSL | |
| SCHEMBL3157965 | 0.80 | F2 (0.60) | F2MASP2 | |
| SCHEMBL1434507 | 0.78 | TACR1 (0.53) | KLKB1CTSL | |
| SCHEMBL1432737 | 0.78 | MAPK14 (0.48) | F2MASP2KLKB1CTSLMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | claimed |
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |