Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433255 | 0.90 | F2 (0.52) | MCHR1F2PYGLMASP2CTSL | |
| SCHEMBL1434012 | 0.89 | PYGL (0.52) | MCHR1F2PYGLCTSLCTNNB1 | |
| SCHEMBL1433077 | 0.85 | PYGL (0.49) | MCHR1F2PYGLCTNNB1KDM4E | |
| SCHEMBL1433533 | 0.84 | PYGL (0.49) | MCHR1F2PYGLCTSLCTNNB1 | |
| SCHEMBL1433111 | 0.81 | F2 (0.53) | F2MASP2CTSL | |
| SCHEMBL1432813 | 0.81 | HDAC3 (0.53) | PYGLKDM4EMAPT | |
| SCHEMBL1433599 | 0.81 | PYGL (0.50) | F2PYGLMASP2CTNNB1 | |
| SCHEMBL1432834 | 0.80 | PYGL (0.53) | MCHR1PYGLCTSLCTNNB1KDM4E | |
| SCHEMBL1435079 | 0.79 | PYGL (0.52) | MCHR1PYGLCTSLCTNNB1KDM4E | |
| SCHEMBL1433554 | 0.78 | PYGL (0.52) | F2PYGLCTSLCTNNB1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |