Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 15/20 | 0.47 |
| ▸ | CTSS | P25774 | 15/20 | 0.47 |
| ▸ | CTSV | O60911 | 14/20 | 0.47 |
| ▸ | CTSK | P43235 | 12/20 | 0.47 |
| ▸ | CTSB | P07858 | 9/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434709 | 0.89 | F2 (0.51) | F2KLKB1CTSBMASP2 | |
| SCHEMBL1433111 | 0.88 | F2 (0.53) | F2KLKB1CTSLMASP2 | |
| SCHEMBL1434049 | 0.87 | KLKB1 (0.47) | F2KLKB1MASP2 | |
| SCHEMBL1433449 | 0.86 | KLKB1 (0.57) | KLKB1CTSLCTSSCTSVCTSK | |
| SCHEMBL1433554 | 0.84 | PYGL (0.52) | F2CTSLCTSSCTSVCTSK | |
| SCHEMBL1434273 | 0.84 | F2 (0.50) | F2KLKB1CTSSCTSKMASP2 | |
| SCHEMBL1434012 | 0.80 | PYGL (0.52) | F2CTSLCTSS | |
| SCHEMBL1434507 | 0.80 | TACR1 (0.53) | KLKB1CTSL | |
| SCHEMBL3157747 | 0.79 | F2 (0.59) | F2KLKB1MASP2 | |
| SCHEMBL3149506 | 0.79 | F2 (0.59) | F2KLKB1MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |