Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 3/20 | 0.41 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CPB1 | P15086 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433254 | 0.86 | CPB2 (0.44) | MASP2F2 | |
| SCHEMBL1901776 | 0.83 | CYP3A4 (0.37) | F2MEN1KMT2ACYP3A4 | |
| SCHEMBL1906926 | 0.83 | CYP3A4 (0.37) | F2MEN1KMT2ACYP3A4 | |
| SCHEMBL1870522 | 0.82 | MASP2 (0.45) | MASP2METTL3 | |
| SCHEMBL1432393 | 0.81 | MASP2 (0.43) | MASP2PPIBCPB1METTL3 | |
| SCHEMBL1432406 | 0.81 | MASP2 (0.43) | MASP2PPIBCPB1METTL3 | |
| SCHEMBL1431929 | 0.81 | MASP2 (0.46) | MASP2PPIBCYP3A4CPB1ALDH1A1 | |
| SCHEMBL6882736 | 0.81 | MASP2 (0.43) | MASP2PPIBCYP3A4CPB1ALDH1A1 | |
| SCHEMBL1432619 | 0.81 | MASP2 (0.42) | MASP2PPIBCYP3A4CPB1MAPK14 | |
| SCHEMBL3139463 | 0.81 | MASP2 (0.46) | MASP2PPIBCYP3A4CPB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300428-A1 | AMINOPYRIDINE DERIVATIVES | Vantia Limited (GB) | 2011-03-30 | — | — | EP | disclosed |
| WO-2009133348-A1 | AMINOPYRIDINE DERIVATIVES | VANTIA LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |