Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1433401 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL14622160 | 0.85 | ALDH1A1 (0.68) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL3480459 | 0.85 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL7694742 | 0.84 | KDM4E (0.73) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL978291 | 0.83 | KDM4E (0.71) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL7172752 | 0.82 | ALDH1A1 (0.67) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL1432938 | 0.82 | ALDH1A1 (0.72) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL11786444 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10754121 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL1434097 | 0.81 | KDM4E (0.64) | KDM4EALDH1A1CYP1A2CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675448-A | Chlorination process | ETHYL CORPORATION (US) | 1987-06-23 | — | — | US | claimed |
| US-4642384-A | Process for the preparation of derivatives of pyrrolidine and piperidine | RIKER LABORATORIES, INC. (US) | 1987-02-10 | — | — | US | claimed |
| JP-1125343-A | — | — | None | — | — | JP | disclosed |
| JP-1125343-A | — | — | None | — | — | JP | disclosed |
| EP-1907360-B1 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | GLADE ORGANICS PRIVATE LTD (IN) | 2011-03-30 | — | — | EP | disclosed |
| US-20100184990-A1 | Process for the Manufacture of Flecainide | GLADE ORGANICS PRIVATE LIMITED (IN) | 2010-07-22 | — | — | US | disclosed |
| US-20100184990-A1 | Process for the Manufacture of Flecainide | GLADE ORGANICS PRIVATE LIMITED (IN) | 2010-07-22 | — | — | US | disclosed |
| US-20100184990-A1 | Process for the Manufacture of Flecainide | GLADE ORGANICS PRIVATE LIMITED (IN) | 2010-07-22 | — | — | US | disclosed |
| EP-1907360-A4 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | GLADE ORGANICS PRIVATE LTD (IN) | 2009-04-01 | — | — | EP | disclosed |
| EP-1907360-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | Glade Organics Private Limited (IN) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007003982-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF FLECAINIDE | GLADE ORGANICS PRIVATE LIMITED (IN) | 2007-01-11 | — | — | WO | disclosed |
| JP-H01125343-A | 2,5-BIS(2,2,2-TRIFLUOROETHOXY)-ALPHA,ALPHA,ALPHA-TRICHLOROACETOPHENONE AND ITS PRODUCTION | RIKER LAB INC | 1989-05-17 | — | — | JP | disclosed |
| JP-H01125343-A | 2,5-BIS(2,2,2-TRIFLUOROETHOXY)-ALPHA,ALPHA,ALPHA-TRICHLOROACETOPHENONE AND ITS PRODUCTION | RIKER LAB INC | 1989-05-17 | — | — | JP | disclosed |
| US-4675448-A | Chlorination process | ETHYL CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| US-4675448-A | Chlorination process | ETHYL CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |
| US-4650873-A | Process for the preparation of a derivative of piperidine | RIKER LABORATORIES (US) | 1987-03-17 | — | — | US | disclosed |
| US-4642384-A | Process for the preparation of derivatives of pyrrolidine and piperidine | RIKER LABORATORIES, INC. (US) | 1987-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184990-A1 | Process for the Manufacture of Flecainide | KCND2, KCNH1, KCNH2 | KDM4E 478/4885ALDH1A1 960/4885CYP1A2 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.