Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31599525 | 1.00 | CES2 (0.54) | CES2CES1BCHE | |
| SCHEMBL21262449 | 0.82 | CES2 (0.40) | CES2CES1BCHE | |
| SCHEMBL8281293 | 0.82 | CES2 (0.35) | CES2CES1 | |
| SCHEMBL16956339 | 0.80 | CES2 (0.58) | CES2CES1BCHE | |
| SCHEMBL14040983 | 0.79 | CES2 (0.56) | CES2CES1BCHE | |
| SCHEMBL1808758 | 0.78 | CES2 (0.56) | CES2CES1BCHE | |
| SCHEMBL22640332 | 0.77 | CES2 (0.31) | CES2CES1 | |
| SCHEMBL17128930 | 0.77 | CA12 (0.43) | CES2CES1 | |
| SCHEMBL671906 | 0.76 | CES2 (0.67) | CES2CES1BCHE | |
| SCHEMBL29775631 | 0.76 | CES2 (0.67) | CES2CES1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12404253-B2 | 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR1 | ASTRAZENECA AB (SE) | 2025-09-02 | — | — | US | disclosed |
| EP-4605388-A1 | <SUP2/>? <SUB2/>?3?2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CXCR1 | Astrazeneca AB (SE) | 2025-08-27 | — | — | EP | disclosed |
| US-20240383866-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | ASTRAZENECA AB (SE) | 2024-11-21 | — | — | US | disclosed |
| US-20240199558-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | ASTRAZENECA AB (SE) | 2024-06-20 | — | — | US | disclosed |
| WO-2024083933-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX 3CR1 | ASTRAZENECA AB (SE) | 2024-04-25 | — | — | WO | disclosed |
| EP-1893323-B1 | A METHOD OF PREPARING A RADIATION FUEL CELL MEMBRANE WITH ENHANCED CHEMICAL STABILITY AND A MEMBRANE ELECTRODE ASSEMBLY | SCHERRER INST PAUL (CH) | 2011-03-30 | — | — | EP | disclosed |
| US-20080199754-A1 | Method for Preparing a Radiation Grafted Fuel Cell Membrane with Enhanced Chemical Stability and a Membrane Electrode Assembly | PAUL SCHERRER INSTITUT (CH) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199558-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | CX3CR1, CCR2, CCR5 | CES2 3829/4885CES1 4432/4885BCHE 4871/4885 |
| US-20240383866-A1 | 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 | CX3CR1, CCR2, CCR5 | CES2 3829/4885CES1 4432/4885BCHE 4871/4885 |
| US-12404253-B2 | 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR1 | CX3CR1, CCR2, CCR5 | CES2 3829/4885CES1 4432/4885BCHE 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.