Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335162 | 0.87 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3R1 | |
| SCHEMBL14334926 | 0.80 | ROCK2 (0.46) | — | |
| SCHEMBL14334913 | 0.80 | ROCK2 (0.48) | — | |
| SCHEMBL14334120 | 0.78 | ROCK2 (0.48) | — | |
| SCHEMBL3673425 | 0.77 | GRM4 (0.50) | — | |
| SCHEMBL14334239 | 0.76 | ROCK2 (0.50) | — | |
| SCHEMBL3675210 | 0.73 | ROCK2 (0.47) | — | |
| SCHEMBL31234741 | 0.72 | NAMPT (0.44) | PIK3CDPIK3CA | |
| SCHEMBL23458839 | 0.72 | ROCK2 (0.53) | — | |
| SCHEMBL20646781 | 0.71 | RAB9A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012176123-A1 | 3 - IMIDAZOLYL- INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2012-12-27 | — | — | WO | disclosed |