Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810821 | 0.92 | L3MBTL1 (0.57) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL17798298 | 0.88 | TSHR (0.61) | TSHRALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6057368 | 0.85 | LMNA (0.64) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL811440 | 0.85 | TDP1 (0.61) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL14335405 | 0.84 | SMN1; SMN2 (0.61) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL810857 | 0.83 | TDP1 (0.59) | CHRM2CHRM4CHRM1CHRM3RAB9A | |
| SCHEMBL13974641 | 0.83 | TSHR (0.56) | TSHRMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL14335520 | 0.83 | LMNA (0.53) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL198523 | 0.83 | ESR1 (0.59) | HPGDCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL28951399 | 0.83 | TYR (0.54) | CHRM2CHRM4CHRM1CHRM3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723780-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-04-26 | — | — | EP | disclosed |
| CN-103781805-B | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限责任公司 | 2016-10-12 | — | — | CN | disclosed |
| US-9034783-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2015-05-19 | — | — | US | disclosed |
| US-20140142262-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.I. (IT) | 2014-05-22 | — | — | US | disclosed |
| CN-103781805-A | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE SRL | 2014-05-07 | — | — | CN | disclosed |
| EP-2723780-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2014-04-30 | — | — | EP | disclosed |
| WO-2012175425-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2012-12-27 | — | — | WO | disclosed |