Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | APP | P05067 | 4/20 | 1.00 |
| ▸ | SNCA | P37840 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | RBP4 | P02753 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 1/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.80 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.80 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | DRD3 | P35462 | 2/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Retinol SCHEMBL15592 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL1580302 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL3113 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL19660979 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL3112 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Zuretinol SCHEMBL254333 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL15593 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL8360234 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL14619410 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA | |
| Retinol SCHEMBL17226 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MAPTCYP3A4APPSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2208510-B1 | Cosmetic or dermatological composition comprising a retinoid, a non-phosphated compound based on adenosine and a semi-crystalline polymer | OREAL (FR) | 2011-03-30 | — | — | EP | disclosed |
| EP-2208510-A1 | Cosmetic or dermatological composition comprising a retinoid, a non-phosphated compound based on adenosine and a semi-crystalline polymer | L'OREAL (FR) | 2010-07-21 | — | — | EP | disclosed |
| EP-1804788-A4 | DETECTION AND ANALYSIS OF OPHTHALMICALLY-RELEVANT FLUORESCENT MOLECULES | SIRION THERAPEUTICS INC (US) | 2008-05-21 | — | — | EP | disclosed |
| EP-1804788-A2 | DETECTION AND ANALYSIS OF OPHTHALMICALLY-RELEVANT FLUORESCENT MOLECULES | Sirion Therapeutics, Inc. (US) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006047475-A2 | DETECTION AND ANALYSIS OF OPHTHALMICALLY-RELEVANT FLUORESCENT MOLECULES | SYTERA, INC. (US) | 2006-05-04 | — | — | WO | disclosed |
| EP-1201228-B1 | Cosmetic composition containing a retinoid and a silicone benzotriazol | OREAL (FR) | 2004-08-18 | — | — | EP | disclosed |
| EP-1201228-A1 | Cosmetic composition containing a retinoid and a silicone benzotriazol | L'OREAL (FR) | 2002-05-02 | — | — | EP | disclosed |