Retinol

Retinol

SCHEMBL14619410

CC1=C(/C=C/C(C)=C/C=C\C(C)=C/CO)C(C)(C)CCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
MAPT P10636 7/20 1.00
CYP3A4 P08684 6/20 1.00
APP P05067 4/20 1.00
SNCA P37840 4/20 1.00
ALOX15 P16050 3/20 1.00
MAPK1 P28482 3/20 1.00
RBP4 P02753 3/20 1.00
TSHR P16473 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
NR1I2 O75469 1/20 1.00
USP2 O75604 1/20 1.00
PTGS1 P23219 4/20 0.80
SLCO1B3 Q9NPD5 2/20 0.80
SLCO1B1 Q9Y6L6 2/20 0.80
LMNA P02545 2/20 0.80
DRD3 P35462 2/20 0.80
TDP1 Q9NUW8 2/20 0.73
TP53 P04637 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Retinol SCHEMBL15592 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1580302 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3113 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL19660979 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3112 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1433566 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Zuretinol SCHEMBL254333 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL15593 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL8360234 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL17226 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-09-25 US disclosed
EP-4577516-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP disclosed
EP-4577517-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2025-07-02 EP disclosed
WO-2024042131-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2024-02-29 WO disclosed
WO-2024042132-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF BASF SE (DE) 2024-02-29 WO disclosed
WO-2007019503-A2 MANAGEMENT OF OPHTHALMOLOGIC DISORDERS, INCLUDING MACULAR DEGENERATION PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296906-A1 METHOD FOR PREPARING 4-HYDROXY-2-METHYLENE-BUTANAL, 4-HYDROXY-2-METHYL-BUT-2-ENAL AND ESTERS THEREOF ALDH1A2, ADH4, RBP4 ALDH1A1 21/4885MAPT 4478/4885CYP3A4 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.