Retinol

Retinol

SCHEMBL17226

CC(C=CC1=C(C)CCCC1(C)C)=CC=C/C(C)=C/CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
MAPT P10636 7/20 1.00
CYP3A4 P08684 6/20 1.00
APP P05067 4/20 1.00
SNCA P37840 4/20 1.00
ALOX15 P16050 3/20 1.00
MAPK1 P28482 3/20 1.00
RBP4 P02753 3/20 1.00
TSHR P16473 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
NR1I2 O75469 1/20 1.00
USP2 O75604 1/20 1.00
PTGS1 P23219 4/20 0.80
SLCO1B3 Q9NPD5 2/20 0.80
SLCO1B1 Q9Y6L6 2/20 0.80
LMNA P02545 2/20 0.80
DRD3 P35462 2/20 0.80
TDP1 Q9NUW8 2/20 0.73
TP53 P04637 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Retinol SCHEMBL15592 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1580302 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3113 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL19660979 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3112 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1433566 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Zuretinol SCHEMBL254333 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL15593 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL8360234 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL14619410 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700128-A1 MICROBIAL OIL COMPOSITION COMPRISING RETINOIDS AND FATTY ACIDS CJ Cheiljedang Corporation (KR) 2026-02-25 EP claimed
EP-4594492-A1 MODIFIED DOUBLE-STRANDED RNA AGENTS Alnylam Pharmaceuticals, Inc. (US) 2025-08-06 EP claimed
US-12252724-B2 Biosynthesis of retinoids DSM IP ASSETS B.V. (NL) 2025-03-18 US claimed
WO-2024225818-A1 MICROBIAL OIL COMPOSITION COMPRISING RETINOIDS AND FATTY ACIDS 씨제이제일제당 (주) 2024-10-31 WO claimed
EP-4373937-A1 METABOLIC DISORDER-ASSOCIATED TARGET GENE IRNA COMPOSITIONS AND METHODS OF USE THEREOF Alnylam Pharmaceuticals, Inc. (US) 2024-05-29 EP claimed
WO-2024085763-A1 AN IN VITRO METHOD FOR PRODUCING A 3D-STRUCTURE OF CELLS UNIVERSITEIT MAASTRICHT (NL) 2024-04-25 WO claimed
WO-2024073732-A1 MODIFIED DOUBLE-STRANDED RNA AGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2024-04-04 WO claimed
WO-2024042550-A1 OPHTHALMIC COMBINATION COMPOSITION SENTISS PHARMA PRIVATE LIMITED (IN) 2024-02-29 WO claimed
US-20230304002-A1 TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES BANK OF AMERICA, N.A. 2023-09-28 US claimed
US-20230227862-A1 BIOSYNTHESIS OF RETINOIDS DSM IP ASSETS B.V. (NL) 2023-07-20 US claimed
EP-0725623-A1 COSMETIC COMPOSITION COMPRISING A HYDROCALCHONE AND OPTIONALLY RETINOL OR A DERIVATIVE THEREOF UNILEVER PLC (GB) 1996-08-14 EP claimed
US-5545399-A MIXTURE OF HYDROCHALCONE DERIVATIVE AND RETINOL OR DERIVATIVE THEREOF CHESEBROUGH-POND'S USA CO. (US) 1996-08-13 US claimed
US-5489611-A ADMINISTERING A RETINOID COMPOUND WARNER-LAMBERT COMPANY (US) 1996-02-06 US claimed
EP-0666735-A1 RETINOL CONTAINING COSMETIC COMPOSITION UNILEVER PLC (GB) 1995-08-16 EP claimed
EP-0662818-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1995-07-19 EP claimed
WO-1995011662-A1 COSMETIC COMPOSITION COMPRISING A HYDROCALCHONE AND OPTIONALLY RETINOL OR A DERIVATIVE THEREOF UNILEVER PLC (GB) 1995-05-04 WO claimed
WO-1994009756-A1 RETINOL CONTAINING COSMETIC COMPOSITION UNILEVER PLC (GB) 1994-05-11 WO claimed
WO-1994007462-A1 COSMETIC COMPOSITION CONTAINING RETINOL UNILEVER PLC (GB) 1994-04-14 WO claimed
EP-0397774-A1 FORMULATION AND USE OF RETINOIDS IN TREATMENT OF CANCER AND OTHER DISEASES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1990-11-22 EP claimed
WO-1989006977-A1 FORMULATION AND USE OF RETINOIDS IN TREATMENT OF CANCER AND OTHER DISEASES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1989-08-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230304002-A1 TRANSTHYRETIN (TTR) iRNA COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATING OR PREVENTING TTR-ASSOCIATED OCULAR DISEASES TTR, MTPN, CRYAA ALDH1A1 1700/4885MAPT 293/4885CYP3A4 4772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.