Retinol

Retinol

SCHEMBL3113

CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CCO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 1.00
MAPT P10636 7/20 1.00
CYP3A4 P08684 6/20 1.00
APP P05067 4/20 1.00
SNCA P37840 4/20 1.00
ALOX15 P16050 3/20 1.00
MAPK1 P28482 3/20 1.00
RBP4 P02753 3/20 1.00
TSHR P16473 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
NR1I2 O75469 1/20 1.00
USP2 O75604 1/20 1.00
PTGS1 P23219 4/20 0.80
SLCO1B3 Q9NPD5 2/20 0.80
SLCO1B1 Q9Y6L6 2/20 0.80
LMNA P02545 2/20 0.80
DRD3 P35462 2/20 0.80
TDP1 Q9NUW8 2/20 0.73
TP53 P04637 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Retinol SCHEMBL15592 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1580302 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL19660979 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL3112 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL1433566 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Zuretinol SCHEMBL254333 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL15593 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL8360234 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL14619410 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA
Retinol SCHEMBL17226 1.00 ALDH1A1 (1.00) ALDH1A1MAPTCYP3A4APPSNCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 319426 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436416-B1 None US claimed
EP-4483870-A2 AQUEOUS RETINOL FORMULATIONS Orphanix GmbH (AT) 2025-01-01 EP claimed
EP-4479020-A1 KIT OF COSMETIC COMPOSITIONS The Boots Company PLC (GB) 2024-12-25 EP claimed
CN-114574592-B Microbial marker for predicting reproductive performance of male ruminants and application thereof 内蒙古大学 2024-12-17 CN claimed
CN-119033628-A Ethosome, preparation method, application and skin care product 深圳市护家科技有限公司 2024-11-29 CN claimed
EP-4035651-B1 DEPIGMENTING DERMOPHARMACEUTICAL OR COSMETIC COMPOSITION AND USE THEREOF MESOESTETIC PHARMA GROUP S L (ES) 2024-11-27 EP claimed
CN-118986753-A Hydrogen-rich water bicontinuous microemulsion and preparation method and application thereof 研其悦(上海)生物科技有限公司 2024-11-22 CN claimed
WO-2024238869-A1 SKIN CARE SERUM COMPOSITION WITH NATURAL POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2024-11-21 WO claimed
WO-2024234295-A1 COMPOSITION FOR CARING FOR THE KERATIN MATERIALS L'OREAL (FR) 2024-11-21 WO claimed
US-20240382460-A1 Compositions and Methods for Preventing or Improving Premature Skin Aging NANJING NUTRABUILDING BIO-TECH CO., LTD. (CN) 2024-11-21 US claimed
US-3962416-A Preserved nutrients and products KATZEN SOL 1976-06-08 US claimed
US-3957966-A VINYLPYRROLIDONE POLYMER, PLASTICIZER GAF CORPORATION (US) 1976-05-18 US claimed
US-3950418-A DERMATOLOGY HOFFMANN-LA ROCHE INC. (US) 1976-04-13 US claimed
US-3950546-A ALUMINUM SILICATE, SODIUM BENTONITE MUSIC CITY SUPPLEMENT COMPANY (US) 1976-04-13 US claimed
US-3949006-A Synthesis of vitamin A, intermediates and conversion thereof to vitamin A SCM CORPORATION (US) 1976-04-06 US claimed
US-3947596-A Free-flowing, high density, agglomerated vitamin A powder compositions HOFFMANN-LA ROCHE INC. (US) 1976-03-30 US claimed
US-3946115-A GRINDING, EXTRUSION RALSTON PURINA COMPANY (US) 1976-03-23 US claimed
US-3946109-A THYROXINE, VITAMIN A, E, OR T KOLB ERNST 1976-03-23 US claimed
US-3932634-A High potency vitamin water dispersible formulations PFIZER INC. (US) 1976-01-13 US claimed
US-3932546-A Preparation of polyenes MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1976-01-13 US claimed