SCHEMBL14337288

SCHEMBL14337288

C(=N/C1CCCCC1)\c1cnc[nH]1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 6/20 0.46
HRH4 Q9H3N8 2/20 0.41
KMT2A Q03164 1/20 0.41
HTR3A P46098 1/20 0.41
CACNA1B Q00975 1/20 0.40
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
AOC1 P19801 2/20 0.36
KDM4E B2RXH2 1/20 0.35
BLM P54132 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TLK2 Q86UE8 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
CYP19A1 P11511 1/20 0.34
CYP11B1 P15538 1/20 0.34
CYP11B2 P19099 1/20 0.34
MPI P34949 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12372005 0.71 KMT2A (0.47) KMT2AALDH1A1MAPTKDM4EBLM
SCHEMBL14337283 0.69 KMT2A (0.44) KMT2AALDH1A1MAPTKDM4EBLM
SCHEMBL4541953 0.67
SCHEMBL4541956 0.67
SCHEMBL14337257 0.67 HRH4 (0.42) HRH3HRH4HTR3AALDH1A1
SCHEMBL14337243 0.66 KMT2A (0.45) KMT2ACACNA1BALDH1A1MAPTTSHR
SCHEMBL14337250 0.66 KMT2A (0.41) KMT2ACACNA1BALDH1A1MAPTTLK2
SCHEMBL14337276 0.65 LMNA (0.41) KMT2ACACNA1BALDH1A1MAPTTSHR
SCHEMBL27905578 0.62 HRH3 (0.68) HRH3HRH4HTR3AALDH1A1CYP3A4
SCHEMBL27111067 0.61 AOC1 (0.35) HRH3KMT2AALDH1A1AOC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed