SCHEMBL14337276

SCHEMBL14337276

C(=N/C1CCCCC1)\c1ccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 8/20 0.37
MAPT P10636 4/20 0.37
MPI P34949 1/20 0.37
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.34
CACNA1B Q00975 1/20 0.32
POLB P06746 1/20 0.32
NPC1 O15118 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
RAB9A P51151 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14337243 0.71 KMT2A (0.45) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL28259545 0.68 KMT2A (0.67) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL8418574 0.68 KMT2A (0.67) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL8418576 0.68 KMT2A (0.67) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL12372005 0.67 KMT2A (0.47) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL14081797 0.67 AMY1A (0.51) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL8415735 0.66 KMT2A (0.63) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL8415734 0.66 KMT2A (0.63) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL14337283 0.65 KMT2A (0.44) LMNASMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL14337288 0.65 HRH3 (0.46) KMT2AALDH1A1MAPTMPICACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed