SCHEMBL14337359

SCHEMBL14337359

C(=N/c1ccccc1)\c1nnn[nH]1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.42
ALDH1A1 P00352 6/20 0.36
KDM4E B2RXH2 2/20 0.36
GLA P06280 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RAB9A P51151 4/20 0.36
NPC1 O15118 3/20 0.36
NR4A1 P22736 1/20 0.35
MAPT P10636 7/20 0.34
KMT2A Q03164 5/20 0.34
MEN1 O00255 4/20 0.34
CYP1A2 P05177 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
GAA P10253 2/20 0.34
PTGS2 P35354 2/20 0.34
PTGS1 P23219 1/20 0.34
USP2 O75604 1/20 0.34
ALOX12 P18054 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3656377 0.71 KMT2A (0.34) ALDH1A1KDM4EL3MBTL1RAB9ANPC1
SCHEMBL14337198 0.67 MAOA (0.42) MAOAALDH1A1KDM4EGLAL3MBTL1
SCHEMBL9537543 0.66 ALDH1A1 (0.36) ALDH1A1KDM4EL3MBTL1RAB9ANPC1
SCHEMBL14337278 0.64 MAOA (0.47) MAOAALDH1A1KDM4EGLAL3MBTL1
SCHEMBL14129042 0.64 ALDH1A1 (0.69) MAOAALDH1A1KDM4EGLAL3MBTL1
SCHEMBL13084384 0.64 ALDH1A1 (0.63) MAOAALDH1A1KDM4EGLAL3MBTL1
SCHEMBL59999 0.64 ALDH1A1 (0.63) MAOAALDH1A1KDM4EGLAL3MBTL1
SCHEMBL60000 0.64 ALDH1A1 (0.63) MAOAALDH1A1KDM4EGLAL3MBTL1
SCHEMBL14128958 0.63 NPC1 (0.46) MAOAALDH1A1KDM4EGLAL3MBTL1
Ammonia Solution, Strong SCHEMBL2273341 0.62 ALDH1A1 (0.61) MAOAALDH1A1KDM4EGLAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
US-7312284-B2 Process for producing polar olefin copolymer and polar olefin copolymer obtained thereby MITSUI CHEMICALS, INC. (JP) 2007-12-25 US disclosed
EP-1832609-A2 Process for producing a copolymer of a non-polar olefin and a polar olefin and the copolymer obtained thereby Mitsui Chemicals, Inc. (JP) 2007-09-12 EP disclosed