Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | PGK2 | P07205 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1203845 | 0.77 | TSHR (0.46) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL6671376 | 0.74 | TSHR (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL15147577 | 0.74 | TSHR (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL969484 | 0.72 | TSHR (0.56) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL3353801 | 0.72 | PGK1 (0.44) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL28674980 | 0.72 | TSHR (0.42) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL29080970 | 0.72 | TSHR (0.42) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL14337805 | 0.72 | TSHR (0.48) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL7594495 | 0.72 | TSHR (0.42) | TSHRALDH1A1CYP3A4MAPK1TDP1 | |
| SCHEMBL12417384 | 0.72 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312347-B2 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-7312347-B2 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-12-25 | — | — | US | disclosed |
| US-20070073065-A1 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-03-29 | — | — | US | disclosed |
| US-20070073065-A1 | Substituted optically active disphosphine compound | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073065-A1 | Substituted optically active disphosphine compound | DHPS, DOHH, DHODH | TSHR 4237/4885ALDH1A1 277/4885CYP3A4 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.