Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9987095 | 0.73 | P2RX7 (0.43) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL15780518 | 0.69 | APLNR (0.41) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL22048023 | 0.68 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2HPGDTSHRKMT2A | |
| SCHEMBL644275 | 0.68 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL24655830 | 0.68 | MAP4K1 (0.40) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL16858760 | 0.66 | CES1 (0.37) | ALDH1A1SMN1; SMN2HPGDKMT2ARAB9A | |
| SCHEMBL31126503 | 0.65 | GRM5 (0.33) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL23021755 | 0.65 | FAAH (0.35) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL19539187 | 0.64 | TLR8 (0.44) | ALDH1A1SMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL13528328 | 0.63 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867638-A1 | Procedure for the Conection of two Molecules via Diels-Alder Reactions with Inverse Electron Demand | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2007-12-19 | — | — | EP | disclosed |