Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059057 | 0.88 | HPGD (0.52) | SMPD1KMT2AGAAHSD17B10HPGD | |
| SCHEMBL5858634 | 0.81 | NR1H4 (0.55) | SMPD1KMT2AGAAHSD17B10HPGD | |
| SCHEMBL1027959 | 0.78 | SMPD1 (0.43) | SMPD1KMT2AGAAHSD17B10HPGD | |
| SCHEMBL37983114 | 0.77 | CA12 (0.62) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL3045083 | 0.77 | CA12 (0.62) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL9435244 | 0.77 | CHRNA1 (0.50) | SMPD1KMT2AGAAHSD17B10HPGD | |
| SCHEMBL9435248 | 0.77 | CHRNA1 (0.50) | SMPD1KMT2AGAAHSD17B10HPGD | |
| SCHEMBL9717443 | 0.76 | GAA (0.77) | SMPD1KMT2AGAAHSD17B10HPGD | |
| SCHEMBL3358074 | 0.75 | TSHR (0.53) | KMT2AGAAHSD17B10HPGDMEN1 | |
| SCHEMBL5135520 | 0.74 | CA12 (0.50) | KMT2AGAAHSD17B10NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867639-A1 | UREA DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND MEDICINAL USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2007-12-19 | — | — | EP | disclosed |