Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.50 |
| ▸ | CHRNG | P07510 | 1/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9435248 | 1.00 | CHRNA1 (0.50) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL5858634 | 0.86 | NR1H4 (0.55) | GAAKMT2AHSD17B10HPGDSMPD1 | |
| SCHEMBL13753881 | 0.81 | HPGD (0.51) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL12760708 | 0.81 | SMN1; SMN2 (0.57) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL21590324 | 0.79 | ALDH1A1 (0.56) | GAAKMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL21590151 | 0.79 | ALDH1A1 (0.56) | GAAKMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL28501877 | 0.79 | ALDH1A1 (0.56) | GAAKMT2AHSD17B10HPGDALDH1A1 | |
| SCHEMBL7833081 | 0.79 | KMT2A (0.43) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL901725 | 0.78 | HPGD (0.52) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL9435241 | 0.78 | HPGD (0.55) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994015920-A1 | BENZANILIDE DERIVATIVES AS 5-HT1D-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1994-07-21 | — | — | WO | disclosed |