SCHEMBL14339263

SCHEMBL14339263

O=P(c1ccc(-c2ccc(P(=O)(c3ccc4ccccc4c3)c3ccc4ccccc4c3)cc2)cc1)(c1ccc2ccccc2c1)c1ccc2ccccc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
GPR84 Q9NQS5 1/20 0.41
UTRN P46939 4/20 0.41
LMNA P02545 1/20 0.41
ALOX5 P09917 1/20 0.41
PTPN1 P18031 1/20 0.40
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CYP2A6 P11509 2/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19444917 0.96 ESR1 (0.44) GSTP1ESR1ESR2CA1CA2
SCHEMBL14339265 0.96 ALDH1A1 (0.44) GSTP1ESR1ESR2CA1CA2
SCHEMBL14339274 0.96 GPR84 (0.44) GSTP1ESR1ESR2CA1CA2
SCHEMBL14339290 0.96 GPR84 (0.44) GSTP1ESR1ESR2CA1CA2
SCHEMBL17451900 0.94 ESR1 (0.42) GSTP1ESR1ESR2CA1CA2
SCHEMBL3833758 0.93 GPR84 (0.45) GSTP1ESR1ESR2CA1CA2
SCHEMBL17451888 0.92 ESR1 (0.50) GSTP1ESR1ESR2CA1CA2
SCHEMBL21503905 0.91 ALDH1A1 (0.47) CA1CA2GPR84LMNAPTPN1
SCHEMBL14339277 0.91 ALDH1A1 (0.47) CA1CA2GPR84LMNAPTPN1
SCHEMBL31212637 0.91 ALDH1A1 (0.47) CA1CA2GPR84LMNAPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1744598-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND MANUFACTURING METHOD THEREOF, ORGANIC COMPOUND CONTAINING PHOSPHORUS AND MANUFACTURING METHOD THEREOF KYUSHU ELECTRIC POWER (JP) 2017-05-31 EP disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof SLCO4C1, SLC10A6, SLC19A2 GSTP1 3164/4885ESR1 263/4885ESR2 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.