SCHEMBL3833758

SCHEMBL3833758

O=P(c1ccc2ccccc2c1)(c1ccc2ccccc2c1)c1ccc2ccccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.45
LMNA P02545 1/20 0.45
PTPN1 P18031 1/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
CYP2A6 P11509 4/20 0.42
CYP1A2 P05177 3/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 3/20 0.42
HSD17B10 Q99714 3/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
GSTP1 P09211 1/20 0.41
HPGD P15428 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339274 0.98 GPR84 (0.44) GPR84LMNAPTPN1CES2CES1
SCHEMBL14339290 0.98 GPR84 (0.44) GPR84LMNAPTPN1CES2CES1
SCHEMBL14339272 0.95 GPR84 (0.42) GPR84LMNAPTPN1CES2CES1
SCHEMBL15566288 0.93 ALDH1A1 (0.47) GPR84LMNAPTPN1CES2CES1
SCHEMBL30544386 0.93 ALDH1A1 (0.47) GPR84LMNAPTPN1CES2CES1
SCHEMBL14339263 0.93 GSTP1 (0.47) GPR84LMNAPTPN1CES2CES1
SCHEMBL14339280 0.93 ALDH1A1 (0.47) GPR84LMNAPTPN1CES2CES1
SCHEMBL14339277 0.93 ALDH1A1 (0.47) GPR84LMNAPTPN1CES2CES1
SCHEMBL21503905 0.93 ALDH1A1 (0.47) GPR84LMNAPTPN1CES2CES1
SCHEMBL31212637 0.93 ALDH1A1 (0.47) GPR84LMNAPTPN1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582691-B2 Poly(arylene ether) compositions and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-09-01 US claimed
JP-4311938-B2 2009-08-12 JP claimed
WO-2008089314-A1 FLAME RETARDANT POLY (ARLENE ETHER) COMPOSITIONS AND ARTICLES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-24 WO claimed
US-20080171817-A1 POLY(ARYLENE ETHER) COMPOSITIONS AND ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-17 US claimed
US-7202311-B2 Phosphine oxide hydroxyarl mixtures with novolac resins for co-curing epoxy resins GREAT LAKES CORPORATION (US) 2007-04-10 US claimed
EP-1363922-B1 NOVEL HYDROXYARYL PHOSPHINE OXIDES MIXTURE, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM GREAT LAKES CHEMICAL CORP (US) 2006-07-26 EP claimed
US-20040225080-A1 Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins GREAT LAKES CHEMICAL CORPORATION 2004-11-11 US claimed
JP-2004533413-A 2004-11-04 JP claimed
US-20040121990-A1 Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom GREAT LAKES CHEMICAL CORPORATION 2004-06-24 US claimed
US-6733698-B2 Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions PABU SERVICES, INC. 2004-05-11 US claimed
EP-1363922-A2 NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM Pabu Services, Inc. (US) 2003-11-26 EP claimed
US-20030148109-A1 Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins CHEMTURA CORPORATION 2003-08-07 US claimed
US-20020168527-A1 Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom GREAT LAKES CHEMICAL CORPORATION 2002-11-14 US claimed
WO-2002066485-A2 NOVEL HYDROXYARYL PHOSPHINE OXIDES, GLYCIDYL ETHERS AND EPOXY COMPOSITIONS, COMPOSITES AND LAMINATES DERIVED THEREFROM PABU SERVICES, INC. (US) 2002-08-29 WO claimed
US-10870724-B2 High heat monomers and methods of use thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-12-22 US disclosed
CN-106660953-B High heat resistant monomers and methods of use thereof 沙特基础工业全球技术有限公司 2020-07-28 CN disclosed
EP-3569591-A1 HIGH HEAT MONOMERS AND METHODS OF USE THEREOF SABIC Global Technologies B.V. (NL) 2019-11-20 EP disclosed
US-20050020801-A1 Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins GREAT LAKES CHEMICAL CORPORATION 2005-01-27 US disclosed
US-20040225080-A1 Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins GREAT LAKES CHEMICAL CORPORATION 2004-11-11 US disclosed
US-20030148109-A1 Phosphine oxide hydroxyaryl mixtures with novolac resins for co-curing epoxy resins CHEMTURA CORPORATION 2003-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040121990-A1 Novel hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom PFAS, PTPMT1, PWWP2B GPR84 1578/4885LMNA 724/4885PTPN1 525/4885
US-10870724-B2 High heat monomers and methods of use thereof HSP90AA1, HSP90AB1, EPHX2 GPR84 4153/4885LMNA 1402/4885PTPN1 4599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.