SCHEMBL14339264

SCHEMBL14339264

O=P(c1ccc(-c2ccc(P(=O)(c3cccc4ccccc34)c3cccc4ccccc34)cc2)cc1)(c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
ACP3 P15309 3/20 0.39
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
PTK2B Q14289 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HDAC8 Q9BY41 2/20 0.37
HDAC6 Q9UBN7 1/20 0.37
TOP1 P11387 1/20 0.36
CYP2A6 P11509 3/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5437709 0.96 LMNA (0.47) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL18780702 0.93 KDM4E (0.41) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL5760742 0.93 TOP1 (0.43) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL14339281 0.92 LMNA (0.45) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL14339289 0.92 KDM4E (0.47) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL17451881 0.91 TOP1 (0.42) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL19857353 0.90 ESR1 (0.43) KDM4ELMNAPOLBACP3CA12
SCHEMBL18372134 0.90 KDM4E (0.39) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL22639332 0.89 ALDH1A1 (0.41) KDM4ELMNAPOLBACP3ALDH1A1
SCHEMBL22639333 0.89 ALDH1A1 (0.41) KDM4ELMNAPOLBACP3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9857705-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-01-02 US disclosed
US-20170115582-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-04-27 US disclosed
US-20170115582-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-04-27 US disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof SLCO4C1, SLC10A6, SLC19A2 KDM4E 1932/4885LMNA 2279/4885POLB 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.