SCHEMBL5437709

SCHEMBL5437709

O=P(c1ccc(P(=O)(c2cccc3ccccc23)c2cccc3ccccc23)cc1)(c1ccc(P(=O)(c2cccc3ccccc23)c2cccc3ccccc23)cc1)c1ccc(P(=O)(c2cccc3ccccc23)c2cccc3ccccc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 1/20 0.47
ACP3 P15309 1/20 0.40
PTK2B Q14289 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 3/20 0.39
CYP2A6 P11509 3/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
MMP3 P08254 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
MMP8 P22894 1/20 0.37
MMP14 P50281 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339264 0.96 KDM4E (0.45) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339281 0.96 LMNA (0.45) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339289 0.96 KDM4E (0.47) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339284 0.92 LMNA (0.45) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339278 0.92 LMNA (0.45) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339276 0.92 LMNA (0.45) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL11451532 0.92 KDM4E (0.47) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL31212642 0.92 KDM4E (0.47) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339295 0.90 LMNA (0.46) LMNAKDM4EPOLBACP3PTK2B
SCHEMBL14339288 0.89 LMNA (0.41) LMNAKDM4EPOLBACP3PTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1744598-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND MANUFACTURING METHOD THEREOF, ORGANIC COMPOUND CONTAINING PHOSPHORUS AND MANUFACTURING METHOD THEREOF KYUSHU ELECTRIC POWER (JP) 2017-05-31 EP disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-9406910-B2 Organic electroluminescent element and manufacturing method thereof, and phosphorus-containing organic compound and manufacturing method thereof DAIDEN CO., LTD (JP) 2016-08-02 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20130295706-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2013-11-07 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof KYUSHU ELECTRIC POWER CO., INC. (JP) 2007-12-20 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed
US-20070228356-A1 ORGANIC-INORGANIC COMPOSITE SEMICONDUCTOR MATERIAL, LIQUID MATERIAL, ORGANIC LIGHT EMITTING ELEMENT, METHOD OF MANUFACTURING ORGANIC LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070290605-A1 Organic Electroluminescent Element and Manufacturing Method Thereof, and Phosphorus-Containing Organic Compound and Manufacturing Method Thereof SLCO4C1, SLC10A6, SLC19A2 LMNA 2279/4885KDM4E 1932/4885POLB 1106/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.