SCHEMBL1433928

SCHEMBL1433928

CC(=O)OC(CCO)CCO

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
PRKCA P17252 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 1/20 0.41
CYP1A2 P05177 1/20 0.41
HRH1 P35367 1/20 0.41
KMT2A Q03164 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM1 P11229 1/20 0.38
TBXA2R P21731 1/20 0.38
MAPT P10636 2/20 0.37
GALR3 O60755 1/20 0.37
BLM P54132 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
TRPV1 Q8NER1 1/20 0.35
MMP12 P39900 1/20 0.35
ALOX15 P16050 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28270101 0.91 PRKCA (0.41) TSHRPRKCASMN1; SMN2MEN1CYP1A2
SCHEMBL28419546 0.91 PRKCA (0.45) TSHRPRKCASMN1; SMN2MEN1CYP1A2
SCHEMBL1434172 0.88 PRKCA (0.42) TSHRPRKCASMN1; SMN2MEN1CYP1A2
SCHEMBL9580116 0.85 PRKCA (0.53) PRKCALMNAMAPTMAPK1GLS2
SCHEMBL7758842 0.84 PRKCA (0.47) TSHRPRKCASMN1; SMN2MEN1CYP1A2
SCHEMBL11654945 0.81 PRKCA (0.49) TSHRPRKCASMN1; SMN2MEN1KMT2A
SCHEMBL11654951 0.81 PRKCA (0.49) TSHRPRKCASMN1; SMN2MEN1KMT2A
SCHEMBL29020020 0.80 PRKCA (0.51) TSHRPRKCASMN1; SMN2MEN1KMT2A
SCHEMBL4838071 0.79 TSHR (0.43) TSHRPRKCASMN1; SMN2MEN1CYP1A2
SCHEMBL24052687 0.78 PRKCA (0.50) PRKCAMAPTMAPK1GLS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1178026-B1 PROCESSES FOR PRODUCING OXIDE WITH HIGHER OXIDATION THAN ALCOHOL OTSUKA KAGAKU KK (JP) 2011-03-30 EP disclosed
US-7183421-B2 Processes for producing oxide with higher oxidation than alcohol OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2007-02-27 US disclosed
US-20050014957-A1 Processes for producing oxide with higher oxidation than alcohol TANAKA HIDEO (JP) 2005-01-20 US disclosed
US-6797830-B2 SILICA GEL CARRIES AN ALCOHOL AND AN OXIDATIVE CATALYST AND OXIDIZING THE ALCOHOL IN THE PRESENCE OF AN OXIDIZER OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2004-09-28 US disclosed
US-20030114712-A1 Process for producing oxide with higher oxidation than alcohol OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2003-06-19 US disclosed
EP-1178026-A1 PROCESSES FOR PRODUCING OXIDE WITH HIGHER OXIDATION THAN ALCOHOL OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 2002-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050014957-A1 Processes for producing oxide with higher oxidation than alcohol ADH1A, NOX4, AOX1 TSHR 4723/4885PRKCA 1025/4885SMN1; SMN2 4671/4885
US-20030114712-A1 Process for producing oxide with higher oxidation than alcohol ADH1A, NOX4, AOX1 TSHR 4719/4885PRKCA 989/4885SMN1; SMN2 4654/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.